Genes, Development And Behavior
Department of Translational Neuroscience
Utrecht, The Netherlands

Student Projects

Molecular biology of axon growth

Aim: identify the molecules that control axon growth
Experimental work: microarray & microRNA array analysis, quantitative PCR, gene cloning, cell biology, gene transfer, neuron culture, microscopy
Contact: Jeroen Pasterkamp

Development of striatal and dopaminergic pathways

Aim: understand how mesostriatal circuits are wired
Experimental work: in situ hybridization, neuroanatomy, immunocytochemistry, FACS and microarray analysis, cell and explant culture, in utero electroporation, genetic mouse models, microscopy
Contact: Jeroen Pasterkamp

Identification of receptor and intracellular signalling proteins involved in axon guidance

Aim: determine how neurons sense and respond to axon growth and guidance cues
Experimental work: proteomics, biochemistry, cell biology, in situ hybridization, neuroanatomy, immunocytochemistry, genetic mouse models, microscopy
Contact: Jeroen Pasterkamp

The molecular basis of ALS

Aim: characterize recently identified ALS susceptibility genes (in collaboration with Department of Neurology, UMC Utrecht)
Experimental work: cell biology, in situ hybridization, neuroanatomy, immunocytochemistry, genetic mouse models, microscopy.
Contact: Jeroen Pasterkamp