Genes, Development And Behavior
Department of Translational Neuroscience
Utrecht, The Netherlands

Student Projects

Biochemical and cell biological properties of Contactin-6

Aim: determine mechanisms of Cntn6 involvement in brain development.

Experimental work: neuronal culturing, cell culturing, immunocytochemistry, DNA cloning, PCR, microscopy, work with knock-out mice.

Contact: Peter Burbach, Amila Zuko

Role of Contactin-5 in the thalamocortical system

Aim: determine the effect of loss-of-function of Cntn5 on the development of the thalamocortical system

Experimental work: immunocytochemistry, confocal microscopy, cell transfection, neuranatomy, brain development, work with knock-out mice, neuronal culturing.

Contact: Peter Burbach, Kristel Kleijer

Consequence of selective loss of Pten in neuronal systems.

Aim: determine the effect of loss-of-function of Pten on the development of the thalamocortical and dopaminergic systems

Experimental work: creating conditional mutant mice, immunocytochemistry, neuranatomy, brain development, work with knock-out mice, neuronal culturing

Contact: Peter Burbach