Translational Neuroscience

The research mission of the Department of Translational Neuroscience is to discover and delineate mechanisms and processes which are fundamental to the development of neural systems and to the control of behavior as well as to translate these to pathogenesis and disease models. We use cutting edge technology, disease models as well as computational tools to achieve these goals.

Our teaching mission is to raise the next generation scientists and clinicians with state-of-the-art knowledge, technical expertise and vision in the field of neuroscience. As a part of this effort, we teach in several Bachelor courses, coordinate the Neuroscience and Cognition master program of the Utrecht University and offer doctoral and postdoctoral training.

News

June 1, 2022 / News, Public outreach

New Scientist Live! Hersenziekten in Tivoli

On Tuesday the 17^th of May UMC Utrecht Brain Center and New Scientist organized ‘NewScientist Live! Hersenziekten in TivoliVredenburg. Several colleagues focused on the technologies of the future. It was an interesting evening, filled with exciting and necessary advances in brain research and patient care.

Tiziana Hey at New Scientist Live! Hersenziekten in Tivoli — Tiziana Hey at New Scientist live, Hersenziekten, technologie van de toekomst
Foto: Bob Bronshoff

Prof. dr. Jeroen Pasterkamp and PhD student Tiziana Hey, from our own Translational Neuroscience department, starred on stage. Jeroen Pasterkamp started the evening off, highlighting important microscopic and organoid research performed in his lab. Tiziana Hey, together with 2 fellow young scientists, closed the evening, explaining research with the use of single cell sequencing techniques. Interested in reading more about this informative evening? You can find a summary of the evening on the website of New Scientist or watch the aftermovie (in Dutch).

“Brain research is like a black box: one big fascinating puzzle” T. Hey

We are very glad to disseminate the knowledge generated at the UMC Utrecth Brain Center.

May 16, 2022 / News

KNAW membership of Elly Hol

Fantastic news from Elly Hol!! The Royal Netherlands Academy of Arts and Sciences (KNAW) announced that Prof. Elly Hol has been chosen as a new member. Members of the KNAW are leading scientists from all disciplines and are chosen on the basis of their scientific achievements. The KNAW has approximately 585 members. A membership is for life. In addition to Elly Hol, 21 other new members have been elected. The new members of the Academy will be installed on 12 September.

“I am very pleased with this recognition for my research on glia. I could not have done this research without the enormous efforts of all PhD students, post-docs, researchers, research analysts, and students who have worked in my group over the years in Amsterdam and Utrecht. It is also really nice to see how the group of glia researchers in the Netherlands and internationally has grown. The collaborations with (inter)national colleagues and the support of subsidy providers make it possible to discover new aspects of neuron-glia interactions in brain diseases. I am also very enthusiastic about new technologies, such as molecular single cell studies on human post-mortem brain material and functional studies in patient mini-brains, which are of great importance for my research on glia in brain diseases.”

We are deeply honoured to have Elly Hol as a group leader at the Translational Neuroscience Department of the UMC Utrecht Brain Center of the UMCU

See the new on the KNAW or Utrecht University webpages

March 31, 2022 / Graduation, News

PhD defence of Andreia Duarte and Lieke van de Haar

Andreia Duarte, after the PhD defence

PhD defence is a special occasion celebrating not only the graduation of a student but also the society gaining a new highly trained specialist. Last week, Andreia Duarte and Lieke van de Haar of the Pasterkamp lab have defended their PhD thesis with two in-person PhD defences at the Academiegebouw of the Utrecht University.

In her work “The Road Less Travelled: Exploring the profile and functions of non-coding RNAs in brain disease, Andreia has explored how circRNAs and tRNAs may facilitate the brain’s response in medial Temporal lobe epilepsy. She has started her new position as an R&D scientist at the VectorY.

“It was a great closure of 4.5 years of work with lots of research, learning, travelling, fun, ending in such an unforgettable day.” Andreia

Lieke built her PhD on a combination of wet lab experiments and computational tools. Her thesis titled “Isles of Molecules” defines the Habenula development at a single cell level and a new mechanism of axonal guidance. We wish her best luck in her new position as a postdoc at the Rajewsky lab at MDC, Germany.

“ It was a great day to celebrate 4,5 years of work at the University Medical Center Utrecht. I very much enjoyed the scientific discussions and having colleagues, friends and family around.” Lieke

The work was performed at our Translational Neuroscience department of the UMC Brain Center. Photographs by Daniëlle van Rossum and Bart van Dijk

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Vacancies

We welcome open applications from PhD candidates and postdocs.