Sarah Swaak
PhD candidate
My research focuses on the origins of tumorigenesis in diffuse midline glioma. By combining cellular barcoding and single-cell RNA sequencing in vitro and in vivo, we aim to retrospectively identify the cell of origin and how regional microenvironmental cues influence tumor development.
iPSC-induced neural stem cell cultures, lentiviral and CRISPR-Cas9 gene editing, genetic barcoding, single-cell RNA sequencing